It is basic medical information of Crohn's disease and Ulcerative colitis.

What's Ulcerative colitis？
Ulcerative colitis principally attacks a mucous membrane in large intestine mucous membrane mainly, and it is said with a disease to wake up cause indistinct colitis to be diffuse for erosion (runup to ulcers) and an ulcer.

There is many it to an adult equal to or less than 30 years old.　There is a little number of patient, but is noted to people of child and 50 years old and over.
There seem to be the young generation and an age peak of a 2 pattern of age.There is not a difference by sexuality, and man and woman rate becomes 1:1.
It is called UC between the persons concerned.
Japanese patient several (number applying for) are 72,672 by the end of 2001.　About 4,000 a year persons are to become sick, and the number of patient continues increasing recently.

The numbers of patients increases led by the in the world European and American various countries.It is said to North Europe and white men, Jews that there are much numbers of patients in particular.It is said to America that there are 550,000 patients in 324000 people, the world.

Is this disease cause elucidated?
There are a lot of opinions such as infection bacterial theory, autoimmunization aberration theory, but a cause is for the present unidentified.
There is the tendency that a symptom becomes bad by stress, and I think that some factors compound and develop it.

There are the mucous stool which jelly-shaped viscous liquid stuck to, blood in stool, a symptom of straining.　In addition, abdominal pain, pyrexia, anorexia, loss of weight are easy to become tired.　A large quantity of active oxygen (free radical) occurs in bowel of the activity period.
When abdomen was made remarkably, the onset of the megacolon that is one of a complication is doubted.　A toxic symptom can be caused, and care is necessary.

A complication happens in a place except bowel (arthrosis and skin or an eye), but a complication out of bowel disappears if a symptom of bowel calms down by a treatment almost.

This disease is classified as follows by region and irradiation of a lesion.
1) proctitis,
2) area nature colitis,
3) left colitis,
4) right side colitis, all
5) colitis
, but there are a little 2) and frequency of 4).

In the activity period, erosion and an ulcer of diffuse continuity, bowel narrow, and elimination of haustra coli (crease of large bowel) is recognized.
In remission (the time when a symptom is relieved), I get edema of bowel and haustra coli recovers and recognizes inflammatory polyp.

By first time seizures type and recrudescence remission type, chronic persistence type, recrudescence remission conformer occupies 85% of the whole and should consider that the people whom large bowel extraction does not operate on recur.

By a classification of seriousness, it is judged in a value of white blood cells and presence of abdominal pain as frequency of
1) diarrhea, presence
2) blood in stool,
3) pyrexia,
4) tachycardia,
5) anemia,
6) blood sedimentation and an assistance item.　
Seriousness is classed in nephrocalcinosis, a serious case, fulminant in mild.
　
When, as for the mild, diarrhea is less than four times in one day, and in degree and the other items where some blood in stool is seen are normal.
The middle class is mild and a severe middle symptom.

A serious case,
1) Diarrhea more than six times for one day,
2) There is blood in stool,
3) Pyrexia more than 37.5 degrees(C),
4) The tachycardia which is more than 90 times for one minute,
5) Haemoglobin less than 10g/dL,
6) Blood sedimentation says a case more than 30mm (one hour, value).


Fulminant,
Diarrhea to be more than 15 times for one day,
2) diarrhoea haemorrhagic,
3) runs hot more than 38 degrees(C) to last,
4), an item of 5) are the same as a serious case, and white blood cells are accompanied with increase more than 10,000/mm ³, strong abdominal pain.

In long-term follow-up example, all colitis type and the potency that it is it in cancer when it is ill and exceeds 10 seem to be high.
The once had better receive a large bowel autoscope diagnosis for one year - two years.

A diagnosis of colitis ulcerative is judged from radiological finding, autoscope findings and biopsy tissue evidence generally.
In a diagnosis, it excludes bacillary dysentery, amoeba dysentery, Schistosoma japonicum, infectious colitis of large bowel tuberculosis and radioactivity enterocolitis, colitis ischaemic, granulomatous colitis, Crohn's disease.
It becomes important that I am the most important diacrisis with Crohn's disease.

Adrenal quality steroid, salazopiline, 5-ASA, immunosuppressive agent, antibiotics are used for a treatment as pharmacotherapy.
With a nutritious meal, I am careful with dairy products and fiber (except a water-soluble dietary fiber), and, for frequent diarrhea, there are the supplying and fluid therapy and enteral nutrient of an electrolyte and moisture when it becomes necessary.
　
←steroido　←Slazopilene　←5-ASA
When it is prescribed Elental (component nutrition agent) with Crohn's disease identically by a hospital, there is a treatment of UC.
Blood transfusion becomes necessary when repeating bloody discharge.
An operation becomes necessary when seeming to be follows.

When even if you undergo a blood transfusion, massive bleeding does not seem to do,Megacolon perforation, canceration, when repeating a recurrence.
There is it when letting an operation finish once, but there are a cleavage operation and a tertiary stage cleavage operation for two times making stoma.
There is progress of surgical instruments, too, and now there seem to be many the second division operations.

The patient whom is operated on for colitis ulcerative, and became stoma cannot receive money of payment from autonomous community .
What you try to ask by no good cause occasionally because it is appearing carbuncle in a rich autonomous community may be good.

There are "avascular necrosis femoral head" or the arthralgia that a bone becomes fragile by using a large quantity of steroid for drug as a complication.
There seems to be only an operation or there is not an effective treatment for "avascular necrosis femoral head" and checks progress or to bury prosthesis.

Development of reaction of "rebound" appears when it cuts steroid freely because a side effect of steroid is afraid of, and pathology turns worse.
Become circulus vitiosus to gain steroid in order to suppress the aggravation.　Would like you consult with a family doctor when reducing steroid and to do cautious loss.
Be under 10mg in particular, and loss of shell has to be cautious.

Steroid suppresses an adrenal function at the same time to suppress inflammation. Because mechanism of adrenal does not conform to it suddenly that a human original function suppressing inflammation (an adrenal role) has cut only steroid from the produced present conditions of balance suddenly, have been defeated by the work that is going to wake up inflammation.
　
There is not pathology in itself that a difference with Crohn's disease has asked you all the large bowel because a lesion is limited to only large bowel.
Now operation operative method developed, and the rate of the people who became an eternity stoma seems to have decreased largely.

As prospective method of treating, there was a method of a leukopheresis treatment, and it was authorized in April, 2000.
Be methods to remove activated white blood cells by a method such as hemodialysis through a filter.
Be good method of treating to the pregnant woman who does not want to use steroid and people disliking a side effect.